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Generic Oxycodone ( Hydrochloride) 80mg x 1 Tablet

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Product Description

General Principles

OxyContin is an opioid agonist first introduced in 1995. It is a Schedule 11 controlled drug used in the treatment of severe pain disorders. OxyContin is a long acting formulation of oxycodone, the medication's active ingredient. Today, various formulations of oxycontin are available.


The drug is a powerful pain killer and widely used in clinical medicine. However, because of its mood altering effects, Oxycontin, like morphine, can be abused and unlawful possession may be subject to criminal prosecution. Over the past decade, OxyContin has become a popular drug and its mood altering effects has led to a significant increase in illicit usage.


Introduction

Besides pain, oxycontin can decrease anxiety, cause euphoria, mental relaxation, respiratory depression, constipation, meiosis (papillary constriction) and suppression of cough. Like all opioid analgesics, with increasing doses there is increasing pain relief. With oxycontin, like morphine, there is no definite maximum dose; the upper limit of pain control is controlled by side effects. The most dangerous side effect is respiratory depression. The precise mechanism of oxycontin is unknown. However, it may interact with opioid receptors located in the brain and spinal cord.


Therapeutic Uses

OxyContin can be used to treat moderate to severe pain associated with:

  • Trauma
  • Injuries
  • Muscle pain
  • Dislocations
  • Fractures
  • Neuralgia
  • Arthritis
  • Lower back pain
  • Pain associated with cancer


Due to the potency of oxycontin and potentially serious side effects, the drug has to be monitored. Treatment should be continuously assessed and adjusted based upon the patient's own reports of pain and side effects and the physician’s clinical judgment.


Since the drug is a controlled substance, a prescription is required to obtain it. Today, it is the most frequently prescribed opioid pain killer in North America.


Dose

OxyContin tablets are available as a controlled-release oral formulation of oxycodone hydrochloride and indicated for the management of moderate to severe pain when a continuous, daily analgesia is needed for a long period of time. The drug is always administered orally. The controlled-release product has a long duration of action (8-12 hours). It is recommended that OxyContin not be used for sporadic pain relief.


OxyContin tablets should be swallowed whole. It is recommended that the tablets not be broken, chewed or crushed, otherwise a rapid release of the drug can occur and lead to severe side effects.


The drug should always be started at the lowest dose in patients who have never been on opioids before or in those patients who are receiving concurrent treatment with muscle relaxants, sedatives, or other CNS depressants. Concomitant analgesia can be provided with non-steroidal anti-inflammatory drugs to minimize side effects. Patients should not receive any other type of opioid drugs while on Oxycontin.


Oxycontin Abuse and Withdrawal

Since the introduction of OxyContin in 1995, there has been a dramatic increase in abuse of this narcotic. Unlike hydrocodone and its derivatives, whose potential for abuse is limited by the presence of aspirin and paracetamol, OxyContin contains only oxycodone. This is an easy drug to abuse by simply crushing the tablet in which the abuser will then ingest, inject, inhale or place rectally. The drug can have serious side effects when injected as it has a prolonged extended action.


Oxycontin is frequently made more available by "doctor shopping," where inpiduals, who do not have a legitimate illness, repeatedly visit many doctors to acquire large amounts of controlled substances. Other methods of obtaining oxycontin include pharmacy persion, robbery, fake or stolen prescription, the internet and improper prescribing practices by physicians.


Recent reports indicate that non-medical use of Oxycontin is relatively high among teenagers. The increased misuse of the drug has led to numerous emergency admissions and even deaths. Many States have introduced legislation to decrease the illegal use of Oxycontin. Numerous States have also introduced prescription monitoring and banned the sale of the drug over the internet.


Despite all the increased efforts by the FDA, DEA, and state or local authorities, the illicit use of Oxycontin is at an all-time high. Over the last decade the increased illicit use of oxycontin has led to the manufacture of “fake” oxycontin pills all over North America.


Sudden stoppage of oxycontin can result in serious withdrawal symptoms. Some of the characters of withdrawal syndrome may include:

  • Restlessness
  • Lacrimation
  • Anxiety
  • Rhinorrhea
  • Yawning
  • Perspiration
  • Chills
  • Myalgia
  • Mydriasis


Other symptoms that might also develop include:

  • Irritability
  • Vague pain
  • Weakness
  • Abdominal cramps
  • Insomnia
  • Nausea
  • Anorexia
  • Vomiting
  • Diarrhea
  • Increased blood pressure
  • Increased respiratory rate
  • Increased heart rate


Both physicians and pharmacies now maintain careful record-keeping of prescribing information including quantity, frequency, and renewal requests. Adequate evaluation of the patient, proper prescribing practices, frequent assessment of pain, proper dispensing and storage are recommended steps that may help limit the abuse of OxyContin.


Side Effects

Respiratory depression is a severe complication of oxycontin. Respiratory depression is a cause of concern in elderly or debilitated patients and usually follows after the use of large initial doses in non-tolerant patients or when other opioids are given concurrently. In the community the majority of OxyContin-related deaths have occurred in inpiduals who were ingesting large quantities of oxycontin in combination with either alcohol or benzodiazepines.


Oxycontin should be used with extreme caution in patients with significant lung disorders such as chronic obstructive pulmonary disease, heart failure or pre-existing respiratory depression. In such patients, even usual therapeutic doses of oxycontin may suppress the respiratory drive to the point of arrest.


OxyContin may cause severe hypotension. There is an added risk to inpiduals whose ability to maintain blood pressure has been compromised by a depleted blood volume, or after concurrent administration with drugs such as phenothiazines or other agents which compromise vasomotor tone. Oxycontin, should be administered with caution to patients in circulatory shock, since vasodilatation produced by the drug may further reduce cardiac output and blood pressure.


Like other opioid narcotics, oxycontin can be fatal at high doses or when combined with other brain depressants such as alcohol.


Precautions

Oxycontin, like all opioid analgesics, has a narrow therapeutic index in certain patient populations, especially in those taking other CNS depressant drugs. Its use should be reserved for cases where the benefits of opioid analgesia outweigh the known risks of respiratory depression, altered mental state, and postural hypotension. The administration of oxycontin may obscure the diagnosis or clinical course in patients with acute abdominal conditions. Oxycontin may aggravate convulsions in patients with seizure disorders.


Contraindications

OxyContin is not indicated for use for intermittent or mild pain after surgery. It is not to be used in cases where the pain is not expected to last a prolonged period of time.


DRUG INTERACTIONS

 

Use with CNS Depressants

OxyContin, like all opioid analgesics, should be used with caution in patients who are concurrently taking other CNS drugs like sedatives, anti-depressants, tranquilizers or alcohol. Combination of oxycontin with these drugs can lead to respiratory depression, hypotension, profound sedation, coma and even death. It is recommended that the smallest dose of oxycontin be used if required in these patients.


Pregnancy

The drug should not be taken by pregnant females and nursing mothers. Neonates whose mothers have been taking oxycontin chronically may exhibit respiratory depression or withdrawal symptoms either at birth or in the nursery. Breast feeding should not be undertaken while a patient is receiving OxyContin because of the possibility of sedation or respiratory depression in the infant.


Pediatric and Elderly Patients

The safety and effectiveness of OxyContin has not been established in pediatric patients below the age of 18. As with all opioids, the starting dose should be reduced to 1/3 to 1/2 of the usual dosage in debilitated, non-tolerant patients. Respiratory depression is the chief hazard in elderly or debilitated patients.


Summary

It is highly recommended that patients receiving OxyContin tablets or their caregivers should be informed about the following:

  1. Oxycontin is a strong pain killer and similar to morphine.
  2. Oxycontin should be ingested whole and not broken, chewed, or crushed due to the risk of a fatal overdose.
  3. If pain persists despite oxycontin, patients should see their physicians to optimize therapy.
  4. The dose of oxycontin should not be changed unless recommended by the physician.
  5. Concerns about abuse and addiction should not deter proper pain management. The development of addiction to opioid analgesics in properly managed patients with pain is rare.

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Product Reviews

  1. she just decided she

    Posted by Yosepha on 12th Feb 2016

    she just decided she didn't want to do it arnmoye. Just like that. I don't think so. I believe she's keeping all her patients whom pay her by cash & who get injections because they bring in the BIG bucks !!So I showed up at her office at 10.am. as she asked. I then proceeded to sit there in pain for 3 hours until she decided it was my turn to see her. Then she gave me the boot !! No warning, & your not gonna tell me she didn't know she was gonna do this last month, so she might have given me a little more time to locate a new doctor. Then she says to me U didn't do anything wrong. I'm just not going to treat U arnmoye . How nice of her.U see the story we were all being told about her cutting patients, was that she was weeding out the people who were selling them or the true addicts who weren't even in real pain. We all agreed with her testing us at random. I had no problem with it. I have nothing to hide. But this witch should've been doing this from the very 1st day she brought us into her practice !! Why was she just taking anybody & everybody in, without testing them or asking for their medical records at least ? Could it have been MONEY ???I thought it was odd myself. It was too easy getting her to take me as a patient. I didn't complain of course, because I was a valid patient & needed the meds. Anyway .Your not supposed to cut off a patient on narcotics long term like this. You send them instantly into withdrawals !! They must know this. And it must be illegal. It is certainly unethical !!This witch, as I'm calling her never gave us an appt. We all had to go into her office at varied times in the morning, on a Saturday only. Then sit & wait for our turn, according to the sign in sheet. She always took IME treatment patients & consults in 1st, no matter when they showed up. And do you know why ? I do !! Because those are the patients who all pay her cash in hand.Since I have Blue Cross, she gets paid her usual fee, minus the co-pay that I pay her. So what did I do wrong ? Have medical coverage ?I just spoke to her billing/info girl the day before I went in. She gave me no hint that I was about to be cut. We were all told that the doctor recently chose this new office for only her medication patients & she would see us all only one day a month there. That was bad enough to know. But to do this on the very 1st appt. day for medication patients ? I mean WTF !!!If I had known I was going to have my head chopped off, I never would've rushed to get there, signed in & waited for 3 hours. As a minor courtesy to the medication patients who were there today, she could have come out to the outer office & announced we were no longer going to be seen by her & we would have to find new doctors asap.She sent me off with one month's worth of meds. So if I can't get in to another doctor within a month, I am screwed !!Thanks to the DEA, there aren't many doctors left to treat the type of pain I have in any other way. If I had another way to do it, I would choose it. There is NO other way !! It means constant suffering, 24/7. No life. No family, no friends. Depression to beat the band. No sleep. No rest. No consoling. Just pure pain & aloneness 'til the day I die. Should I help that day come sooner ? I bet you a lot would and will !!No relief from constant chronic pain is torture for anyone. I have gone the route of every over-the-counter treatment there is and that comes out new. No relief. I have been on assorted prescription medications also. (sans narcotics) tho. It was expensive & very little relief.I have tried several antidepressants. Several anti-eleptics(?). To no avail. And yet, a new doctor will tell me to try it all again. For what ?? To waste money on candy pills ?20 years of this has been enough !! I'm sick of it !!And you idiots who tell us we're nothing but addicts & drug seeking boobs, with no brains had better get yourself back to reality.They created narcotic medication to ease pain. So why shouldn't the doctors use it for that ? No they're told to give us all the expensive crap that's out there, that does nothing for pain. All it does is addict you to it, just like narcotics do. And they curse you with bad side effects besides. They want me to take a medication that adds weight to my body. I fight to keep weight off as a Diabetic. I do not want a drug that makes me fatter !! That would take my Diabetes into cyberspace !! More medications needed. And expensive ones !! Not to mention, the risks to my life in the process. DUHHHH !!!!I am fed up with this system. It has to go !!God pray that none of you or your loved ones ever have to deal with chronic, intractable pain. Maybe then, we'll see a little support from you ?I think the DEA or whoever, should remove the licenses of every doctor who tosses out their patients like I was today. How can they allow them to get away with doing this ? It surely does not follow their doctor's oath.What killed me today in her office was a hoot. She's standing there, knowing I have horrible pain in my feet that can't be relieved any other way but by narcotics & she tells me that her feet hurt !!Well Hell's Bells Doc I'll trade your pain in your feet for mine any day. I said. She laughed and sent me on my way.Oh wait. She did tell me that when I do find a new doctor that she would be happy to forward my records to them. Gee I'm so grateful to her. NOTTTTT !!!!



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